The Histone-H3 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to H3 clustered histone 14, and H3 clustered histone 15. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Histone-H3 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
HIST2H3A,histone cluster 2, H3a.It is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST2H3A is Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation